Which type of cancer is linked to chromium VI exposure?

• A. Skin cancer
• B. Leukemia
• C. Lung cancer
• D. Brain cancer

Answer: (C)

Inhalation exposure to hexavalent chromium is a well-established carcinogenic risk to the lungs. When Cr(VI) compounds are breathed in, the lungs are directly challenged, and over time this exposure increases the likelihood of developing lung cancer. Cr(VI) can enter cells and cause DNA damage through oxidative processes and reactive intermediates formed during cellular reduction, leading to mutations that drive cancer development. This link is strongest in occupational settings such as chrome plating, stainless steel production, pigment manufacturing, and leather tanning, where inhalation exposure is common. While chromium exposure can cause skin irritation and may lead to other issues in different contexts, the cancer type most consistently associated with inhaled Cr(VI) is lung cancer, making it the most accurate answer.